The German Breast Group’s newsroom
Our newsroom provides you with the latest information about the German Breast Group. This section of the website also includes photographic material and information about our events. In addition, our Annual Scientific Reports, which provide an overview of our research activities, can be downloaded here.
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23.07.2018 16th St.Gallen International Breast Cancer Conference 2019
The International Scientific Committee and the local organizers invite to another (16th) outstanding «St. Gallen International Breast Cancer Conference» in Vienna, Austria, from 20-23 March 2019!
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06.07.2018 Review on Endocrine Therapy in Premenopausal HR+/HER2- Metastatic Breast Cancer
Unser Review zur Endokrine Therapie in prämenopausale Patientinnen mit Hormone Rezeptor-positivem, HER2-negativem metastasiertem Brust Krebs wurde in The Oncologist publiziert.
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30.06.2018 Paper of the month: test predicts the risk of recurrence in luminal breast cancer
A translational study including samples from two randomized neoadjuvant GBG trials (GeparTrio and GeparQuattro) that aimed to evaluate a novel test (mEPclin) for predicting the risk of distance recurrence after neoadjuvant chemotherapy in patients with residual estrogen receptor (ER)-positive/HER2-negative breast cancer has been published in the Clinical Cancer Research.
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04.06.2018 ASCO: GeparNuevo Presentation
GeparNuevo Results of primary objective were presented at ASCO 2018: Durvalumab increases the pCR rate in TNBC patients.
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31.05.2018 Paper update: PIK3CA mutations and pCR
PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab
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31.05.2018 Paper of the month: elderly women and neoadjuvant chemotherapy
A pooled analysis using data from eight GBG trials (GeparDuo, GeparTrio pilot and main, GeparQuattro, AGO-1, PREPARE, TECHNO; GeparQuinto) that aimed to help selecting appropriately the elderly women who would benefit from neoadjuvant chemotherapy has been published in the Oncotarget.
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30.04.2018 Paper of the month: survival analysis of the GeparQuinto trial
We are delighted to inform you that the long-term survival analysis of the neoadjuvant GeparQuinto (GBG 44) phase III trial has been published in the Journal of Clinical Oncology.
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30.03.2018 Paper of the month: March 2018
An analysis of 802 women with triple-negative breast cancer (TNBC) from the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) and GeparSixto (GBG 66) trial that investigated the association between the age at TNBC diagnosis and the presence of pathogenic germline BRCA1/2 mutations has been published in the BMC Cancer.
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28.02.2018 Paper of the month: February 2018
The first results of the BrighTNess trial designed to evaluate the addition of veliparib (a PARP inhibitor) plus carboplatin or carboplatin alone to standard neoadjuvant chemotherapy in triple-negative breast cancer (TNBC) have been published in the The Lancet Oncology.
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31.01.2018 Paper of the month: January 2018
A collaborative translational study that included data from six neoadjuvant GBG trials (GeparDuo, GeparTrio, GeparQuattro, GeparQuinto, GeparSixto and GeparSepto) and investigated the role of tumour-infiltrating lymphocytes (TILs) as a prognostic factor in different subtypes of breast cancer after neoadjuvant therapy has been published in the The Lancet Oncology.
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17.08.2017 Effect of BRCA1/2 Status on Response to Neoadjuvant Carboplatin in TNBC
Our paper on mutations analysis in the Geparsixto TNBC-Arm was discussed at ASCO-News.
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05.07.2017 PALOMA-3 Results published
Palbociclib Combined with Fulvestrant in PremenopausalWomen with Advanced Breast Cancer and Prior Progression on Endocrine Therapy: PALOMA-3 Results
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03.02.2017 How Much Information Do We Really Need After Neoadjuvant Therapy for Breast Cancer?
Prof. Loibl and Prof. Denkert discuss "How Much Information Do We Really Need After Neoadjuvant Therapy for Breast Cancer?" in the current JCO Editorial.
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GBG Jahrestreffen und AGO Mamma State of the Art
Vom 2. bis 3. März 2017 findet das GBG Jahrestreffen 2017 und am 4. März das AGO Mamma State of the Art-Meeting statt. Weitere Informationen finden Sie hier.
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31.01.2017 Young Investigator Award
Die GBG vergibt einen Reise zum ESMO in Madrid in 2017 für junge Wissenschaftler. Bewerbung ab sofort möglich.
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08.12.2016 The Lancet - Breast Cancer Series 2016
The introduction of targeted therapies has profoundly changed the course of some subtypes of breast cancer—but many challenges remain. The Lancet’s 2016 Series on breast cancer discusses the most recent advances in the three most common breast cancer subtypes. The first pair of papers focus on the treatment of advanced oestrogen-receptor-positive and HER2-positive breast cancers, while the third describes how an improved understanding of molecular alterations in the heterogeneous and hard-to-treat triple-negative breast cancer may lead to more refined and more effective therapy. http://www.thelancet.com/series/breast-cancer-2016
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08.11.2016 Tailored, Dense-Dose Chemotherapy for Early Breast Cancer Does Not Result in Significant Improvement in Recurrence-Free Survival
Among women with high-risk early breast cancer, the use of tailored dose-dense chemotherapy compared with standard adjuvant chemotherapy did not result in a statistically significant improvement in breast cancer recurrence-free survival, and nonhematologic toxic effects were more frequent in the tailored dose-dense group, according to a study appearing in the November 8 issue of JAMA.
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01.08.2016 GAIN 2 – Amendment 3 – neoadjuvanter Behandlungarm ist geöffnet
Am 01. August 2016 wurde Amendment 3 der Gain 2 Studie live geschaltet. Es beinhaltet die Öffnung für den neoadjuvanten Behandlungszweig. Zur Erreichung des Rekrutierungsziels (2.886 Patienten) wird die Studie bis QIV 2017 für den Einschluss von Patientinnen geöffnet bleiben.
